Cytoskeleton: Centrosom-in absentia

A binding motif for Siah ubiquitin ligase.

The Drosophila SINA (seven in absentia) protein and its mammalian orthologs (Siah, seven in absentia homolog) are RING domain proteins that function in E3 ubiquitin ligase complexes and facilitate ubiquitination and degradation of a wide range of cellular proteins, including beta-catenin. Despite these diverse targets, the means by which SINASiah recognize substrates or binding proteins has rem...

Comparing The Effect of Resuscitation Drugs Training by in-Person and in-Absentia Methods on The Knowledge of Nursing Students Studying in Islamic Azad University, Najafabad Branch, in 2020

Introduction: In half of all cardiac arrests, nurses are the first to begin resuscitation. Therefore, one of the requirements of nurses and nursing students is to acquire the necessary knowledge about the drugs used in resuscitation. The aim of this study was to compare the effect of resuscitation drugs training by in-person and in-absentia methods on the knowledge of nursing students studying ...

Effect of Stress-Fiber Inclusion on the Local Stiffness of Cell Cytoskeleton Probed by AFM Indentation: Insights from a Discrete Network Model

In this paper, we analyze the effect of stress-fiber inclusion on the stiffness of an actin random network. To do this, use a discrete random network model to analyze the elastic response of this system in terms of apparent Young’s modulus. First, we showed that for a flat-ended cylindrical AFM indenter the total indentation force has a linear relation with the indentation depth and the indente...

Warning signal: unaware of an in absentia conviction, South African cancer specialist jailed on return to the United Arab Emirates.

I-6: Role of Actin Cytoskeleton during Mouse Sperm Acrosomal Exocytosis

Background: Mammalian sperm must undergo a process termed capacitation to become competent to fertilize an egg. Capacitation renders the sperm competent by priming the cells to undergo a rapid exocytotic event called acrosomal exocytosis that is stimulated by the zona pellucida (ZP) of the egg or progesterone. Over the years, several biochemical events have been associated with the capacitation...